Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749212 | 0.72 | — | — | |
| SCHEMBL21985479 | 0.71 | TRPV4 (0.35) | NT5EALDH1A1KDM4EHSD17B10TRPV4 | |
| SCHEMBL24027389 | 0.70 | TRPV4 (0.39) | NT5EALDH1A1KDM4EHSD17B10HSP90AA1 | |
| SCHEMBL24589987 | 0.70 | NT5E (0.41) | NT5EALDH1A1KDM4EHSD17B10HSP90AA1 | |
| SCHEMBL24784677 | 0.69 | TRPV4 (0.46) | NT5EALDH1A1KDM4EHSD17B10HSP90AA1 | |
| SCHEMBL6468496 | 0.69 | NT5E (0.42) | NT5EALDH1A1KDM4EHSD17B10HSP90AA1 | |
| SCHEMBL1965945 | 0.69 | KDM4E (0.46) | NT5EALDH1A1KDM4EHSD17B10HSP90AA1 | |
| SCHEMBL18319881 | 0.68 | TDP1 (0.34) | MAPT | |
| SCHEMBL31184211 | 0.68 | TDP1 (0.34) | MAPT | |
| SCHEMBL11985863 | 0.68 | HSP90AA1 (0.42) | NT5EALDH1A1KDM4EHSD17B10HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087699-A | Chemical intermediate for pyridinethiolate nickel complex; light stabilizers, infrared absorbers and chelate compounds | RICOH COMPANY, LTD. (JP) | 1992-02-11 | — | — | US | disclosed |