SCHEMBL9750319

SCHEMBL9750319

NC(=O)NC1CCN(Cc2ccc3cc(F)ccc3c2)CC1

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCR3 P51677 17/20 0.75
MCHR1 Q99705 4/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5307088 0.93 CCR3 (0.76) CCR3MCHR1
SCHEMBL9592011 0.88 MCHR1 (0.74) MCHR1
SCHEMBL18844433 0.86 CCR3 (1.00) CCR3MCHR1
SCHEMBL18844268 0.84 CCR3 (1.00) CCR3MCHR1
SCHEMBL11057431 0.80 CCR3 (0.84) CCR3MCHR1
SCHEMBL18844223 0.80 CCR3 (1.00) CCR3MCHR1
SCHEMBL18841090 0.79 CCR3 (1.00) CCR3MCHR1
SCHEMBL9593130 0.79 CCR3 (0.61) CCR3MCHR1
SCHEMBL9592175 0.79 CCR3 (0.71) CCR3MCHR1
SCHEMBL18844261 0.79 CCR3 (1.00) CCR3MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0234098-B1 N-[piperidylaminocarbonyl]quinolinecarboxamide derivatives having psychotropic activity JOHN WYETH & BROTHER LIMITED (GB) 1992-02-26 EP disclosed
CN-1014411-B Process for preparing N[[[[1-(6-fluo-2-naphthyl) methyl]-4-piperidyl] amino] carboxyl] pyridylcarboxamide WYETH JOHN & BROTHER LTD (GB) 1991-10-23 CN disclosed
US-4778802-A PSYCHOTROPIC ACTIVITY; ANTIDEPRESSANTS JOHN WYETH & BROTHER, LTD. (GB) 1988-10-18 US disclosed
EP-0234098-A1 N-[piperidylaminocarbonyl]quinolinecarboxamide derivatives having psychotropic activity JOHN WYETH & BROTHER LIMITED (GB) 1987-09-02 EP disclosed
CN-86107819-A Heterogeneous ring compound 1987-06-10 CN disclosed