Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 16/20 | 0.71 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.68 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9592427 | 0.90 | MCHR1 (0.70) | CCR3MCHR1DRD4 | |
| SCHEMBL11057431 | 0.90 | CCR3 (0.84) | CCR3MCHR1DRD4 | |
| SCHEMBL9591400 | 0.89 | CCR3 (0.67) | CCR3MCHR1DRD4 | |
| SCHEMBL9792346 | 0.86 | MCHR1 (0.84) | CCR3MCHR1DRD4 | |
| SCHEMBL9748813 | 0.84 | CCR3 (0.62) | CCR3MCHR1DRD4 | |
| SCHEMBL9592845 | 0.83 | DRD4 (0.67) | CCR3MCHR1DRD4 | |
| SCHEMBL18844433 | 0.83 | CCR3 (1.00) | CCR3MCHR1 | |
| Panuramine SCHEMBL2037759 | 0.81 | MCHR1 (0.83) | CCR3MCHR1DRD4 | |
| SCHEMBL9749235 | 0.81 | CCR3 (0.61) | CCR3MCHR1 | |
| Panuramine SCHEMBL9749426 | 0.81 | MCHR1 (0.81) | CCR3MCHR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4806552-A | ANTIDEPRESSANTS | JOHN WYETH & BROTHER, LIMITED (GB) | 1989-02-21 | — | — | US | claimed |
| EP-0228795-A1 | Piperidine derivatives having a psychotropic activity | JOHN WYETH & BROTHER LIMITED (GB) | 1987-07-15 | — | — | EP | claimed |
| CN-86107819-A | Heterogeneous ring compound | — | 1987-06-10 | — | — | CN | claimed |
| US-5212179-A | Antidepressants | JOHN WYETH AND BROTHER LIMITED (GB) | 1993-05-18 | — | — | US | disclosed |
| CN-1014411-B | Process for preparing N[[[[1-(6-fluo-2-naphthyl) methyl]-4-piperidyl] amino] carboxyl] pyridylcarboxamide | WYETH JOHN & BROTHER LTD (GB) | 1991-10-23 | — | — | CN | disclosed |
| US-4985438-A | PSYCHOTROPIC ACTIVITY, ANTIDEPRESSANTS | JOHN WYETH & BROTHER, LIMITED (GB) | 1991-01-15 | — | — | US | disclosed |
| US-4806552-A | ANTIDEPRESSANTS | JOHN WYETH & BROTHER, LIMITED (GB) | 1989-02-21 | — | — | US | disclosed |
| EP-0228795-A1 | Piperidine derivatives having a psychotropic activity | JOHN WYETH & BROTHER LIMITED (GB) | 1987-07-15 | — | — | EP | disclosed |
| CN-86107819-A | Heterogeneous ring compound | — | 1987-06-10 | — | — | CN | disclosed |