Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK2 | O95069 | 2/20 | 0.45 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.45 |
| ▸ | KCNK4 | Q9NYG8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | CBX7 | O95931 | 1/20 | 0.32 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13753893 | 0.85 | KCNK2 (0.44) | KCNK2KCNK10KCNK4ALDH1A1LMNA | |
| SCHEMBL30274468 | 0.83 | KCNK2 (0.45) | KCNK2KCNK10KCNK4ALDH1A1LMNA | |
| SCHEMBL9750249 | 0.82 | KMT2A (0.39) | ALDH1A1LMNASMN1; SMN2KDM4EPGR | |
| SCHEMBL30242144 | 0.82 | PTGDR2 (0.47) | KCNK2KCNK10KCNK4ALDH1A1SMN1; SMN2 | |
| SCHEMBL28980135 | 0.82 | PTGDR2 (0.47) | KCNK2KCNK10KCNK4ALDH1A1SMN1; SMN2 | |
| SCHEMBL4975848 | 0.81 | PTGDR2 (0.47) | KCNK2KCNK10KCNK4ALDH1A1LMNA | |
| SCHEMBL4615673 | 0.78 | ALDH1A1 (0.45) | ALDH1A1LMNASMN1; SMN2KDM4EPTGDR2 | |
| SCHEMBL14341063 | 0.78 | KCNK2 (0.43) | KCNK2KCNK10KCNK4ALDH1A1LMNA | |
| SCHEMBL3809912 | 0.78 | POLB (0.43) | KCNK2KCNK10KCNK4ALDH1A1LMNA | |
| SCHEMBL6091601 | 0.76 | KMT2A (0.46) | ALDH1A1LMNASMN1; SMN2KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120858-A | Condensation of 2-methyleneindoline and formic acid in acetic anhydride | MILES INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0058863-B1 | PROCESS FOR THE PREPARATION OF TRIMETHINE DYESTUFFS | BAYER AG (DE) | 1985-01-23 | — | — | EP | disclosed |
| US-4419511-A | Process for the preparation of trimethine dyestuffs | BAYER AKTIENGESELLSCHAFT (US) | 1983-12-06 | — | — | US | disclosed |
| EP-0058863-A1 | Process for the preparation of trimethine dyestuffs | BAYER AG (DE) | 1982-09-01 | — | — | EP | disclosed |
| US-4201707-A | Methine dyestuffs containing a phenyl azo group | BAYER AKTIENGESELLSCHAFT (DE) | 1980-05-06 | — | — | US | disclosed |
| US-4143228-A | RED SHADES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-06 | — | — | US | disclosed |
| US-4138570-A | METHINE DYE | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-06 | — | — | US | disclosed |