Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 11/20 | 0.65 |
| ▸ | CES1 | P23141 | 10/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27789977 | 0.90 | CES2 (0.59) | CES2CES1TSHRALDH1A1DAO | |
| SCHEMBL1446883 | 0.88 | CES2 (0.56) | CES2CES1TSHRALDH1A1DAO | |
| SCHEMBL7630557 | 0.86 | CES2 (0.54) | CES2CES1TSHRALDH1A1F2 | |
| SCHEMBL1450205 | 0.86 | CES2 (0.54) | CES2CES1TSHRALDH1A1F2 | |
| SCHEMBL7636289 | 0.86 | CES2 (0.54) | CES2CES1TSHRALDH1A1F2 | |
| SCHEMBL1446904 | 0.86 | CES2 (0.54) | CES2CES1TSHRALDH1A1F2 | |
| SCHEMBL7949571 | 0.86 | CES2 (0.54) | CES2CES1TSHRALDH1A1F2 | |
| SCHEMBL16694149 | 0.86 | CES2 (0.54) | CES2CES1TSHRALDH1A1F2 | |
| SCHEMBL9359761 | 0.86 | CES2 (0.54) | CES2CES1TSHRALDH1A1F2 | |
| SCHEMBL6847386 | 0.86 | CES2 (0.54) | CES2CES1TSHRALDH1A1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091171-A | Skin disorders | IGI, INC. | 1992-02-25 | — | — | US | disclosed |