Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10349193 | 0.98 | TSHR (0.50) | TSHRCYP2D6THRBKDM4ESMN1; SMN2 | |
| SCHEMBL27970407 | 0.93 | TSHR (0.55) | TSHRCYP2D6THRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL68168 | 0.89 | THRB (0.47) | TSHRCYP2D6THRBALDH1A1HRH3 | |
| SCHEMBL9292703 | 0.88 | TSHR (0.50) | TSHRCYP2D6THRBKDM4ESMN1; SMN2 | |
| SCHEMBL881770 | 0.88 | KMT2A (0.46) | TSHRTHRBKDM4EALDH1A1MAPT | |
| SCHEMBL68651 | 0.88 | KMT2A (0.46) | TSHRTHRBKDM4EALDH1A1MAPT | |
| SCHEMBL21274378 | 0.88 | KMT2A (0.46) | TSHRTHRBKDM4EALDH1A1MAPT | |
| SCHEMBL27970328 | 0.88 | TSHR (0.58) | TSHRCYP2D6THRBKDM4ESMN1; SMN2 | |
| Bromide SCHEMBL10788752 | 0.86 | KMT2A (0.45) | TSHRTHRBKDM4EALDH1A1MAPT | |
| SCHEMBL27970326 | 0.86 | TSHR (0.61) | TSHRTHRBALDH1A1MAOBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4217905-A | — | — | None | — | — | JP | disclosed |
| JP-H04217905-A | DENTINAL BONDING PROMOTING COMPOUND, PRETREATING AGENT AND BONDING COMPOSITION CONTAINING THE SAME | TERUMO CORP | 1992-08-07 | — | — | JP | disclosed |