Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750592 | 0.85 | KDM4E (0.42) | KDM4EHPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9750626 | 0.80 | KDM4E (0.43) | KDM4EHPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9750597 | 0.77 | KDM4E (0.43) | KDM4EHPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9750549 | 0.76 | KDM4E (0.42) | KDM4EHPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL2790527 | 0.76 | TARBP2 (0.56) | KDM4EHPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9750662 | 0.74 | KDM4E (0.40) | KDM4EHPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL11171845 | 0.74 | CYP1A2 (0.45) | KDM4EHPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9750741 | 0.73 | MAPT (0.49) | KDM4EHPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL2145232 | 0.72 | ADORA3 (0.45) | KDM4EHPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL2145238 | 0.72 | ADORA3 (0.45) | KDM4EHPGDALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5000775-A | 2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1991-03-19 | — | — | US | disclosed |