Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LCAT | P04180 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750598 | 0.88 | KDM4E (0.42) | POLBKDM4EHDAC4HDAC6IDO1 | |
| SCHEMBL9750699 | 0.86 | KDM4E (0.40) | ELANEL3MBTL1KDM4EHDAC4HDAC6 | |
| SCHEMBL9750665 | 0.85 | KDM4E (0.40) | ELANEL3MBTL1KDM4EHDAC4HDAC6 | |
| SCHEMBL9750657 | 0.84 | KDM4E (0.43) | POLBKDM4EHDAC4HDAC6IDO1 | |
| SCHEMBL9750733 | 0.84 | KDM4E (0.39) | KDM4EHDAC4HDAC6IDO1MAPT | |
| SCHEMBL9750647 | 0.82 | KDM4E (0.39) | L3MBTL1KDM4EHDAC4HDAC6IDO1 | |
| SCHEMBL9750615 | 0.82 | KDM4E (0.41) | L3MBTL1KDM4EHDAC4HDAC6IDO1 | |
| SCHEMBL9750603 | 0.81 | ELANE (0.39) | ELANEL3MBTL1KDM4EIDO1MAPT | |
| SCHEMBL9750617 | 0.81 | KDM4E (0.40) | ELANEKDM4EHDAC4HDAC6IDO1 | |
| SCHEMBL9750636 | 0.80 | KDM4E (0.40) | ELANEL3MBTL1KDM4EHDAC4HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5000775-A | 2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1991-03-19 | — | — | US | disclosed |