Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | LCAT | P04180 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750598 | 0.87 | KDM4E (0.42) | KDM4EIDO1ALDH1A1HPGDMAPT | |
| SCHEMBL9750617 | 0.85 | KDM4E (0.40) | KDM4EIDO1ALDH1A1HPGDGAA | |
| SCHEMBL9750699 | 0.85 | KDM4E (0.40) | KDM4EIDO1SLC26A6ALDH1A1HPGD | |
| SCHEMBL9750665 | 0.84 | KDM4E (0.40) | KDM4EIDO1ALDH1A1HPGDMAPT | |
| SCHEMBL9750582 | 0.84 | ELANE (0.46) | KDM4EIDO1ALDH1A1HPGDMAPT | |
| SCHEMBL9750657 | 0.83 | KDM4E (0.43) | KDM4EIDO1ALDH1A1HPGDMAPT | |
| SCHEMBL9750625 | 0.82 | KDM4E (0.39) | KDM4EIDO1ALDH1A1HPGDGAA | |
| SCHEMBL9750647 | 0.81 | KDM4E (0.39) | KDM4EIDO1ALDH1A1HPGDGAA | |
| SCHEMBL9750615 | 0.81 | KDM4E (0.41) | KDM4EIDO1ALDH1A1HPGDMAPT | |
| SCHEMBL9750603 | 0.81 | ELANE (0.39) | KDM4EIDO1ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5000775-A | 2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1991-03-19 | — | — | US | disclosed |