Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | PKM | P14618 | 4/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269359 | 0.82 | GAA (0.49) | GAAKDM4EPKMRCE1ALDH1A1 | |
| SCHEMBL9750567 | 0.77 | MAPK13 (0.49) | GAAKDM4EPKMRCE1ALDH1A1 | |
| SCHEMBL9750634 | 0.74 | CNR2 (0.41) | GAAKDM4EPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL9751005 | 0.74 | GAA (0.47) | GAAKDM4EPKMRCE1ALDH1A1 | |
| SCHEMBL982568 | 0.72 | HCRTR1 (0.47) | GAAKDM4EPKMRCE1ALDH1A1 | |
| SCHEMBL8823173 | 0.69 | GRM6 (0.57) | KDM4EALDH1A1HPGDNPC1CASP3 | |
| SCHEMBL983083 | 0.69 | KDM4E (0.47) | GAAKDM4EPKMRCE1ALDH1A1 | |
| SCHEMBL4380144 | 0.68 | KDM4E (0.68) | GAAKDM4EPKMRCE1ALDH1A1 | |
| SCHEMBL269232 | 0.68 | KDM4E (0.49) | GAAKDM4EPKMRCE1ALDH1A1 | |
| SCHEMBL12482976 | 0.68 | GRM6 (0.49) | GAAKDM4EPKMALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5000775-A | 2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1991-03-19 | — | — | US | disclosed |