Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | PKM | P14618 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL984899 | 0.82 | KDM4E (0.72) | KDM4EALDH1A1PKMSMN1; SMN2L3MBTL1 | |
| SCHEMBL9586961 | 0.81 | KDM4E (1.00) | KDM4EALDH1A1PKMSMN1; SMN2L3MBTL1 | |
| SCHEMBL4368811 | 0.80 | CDC7 (0.51) | KDM4EALDH1A1PKMSMN1; SMN2L3MBTL1 | |
| SCHEMBL4371383 | 0.76 | ALPL (0.49) | KDM4EALDH1A1PKMSMN1; SMN2L3MBTL1 | |
| SCHEMBL18004021 | 0.75 | MAPT (0.55) | KDM4EALDH1A1PKMSMN1; SMN2L3MBTL1 | |
| SCHEMBL3329120 | 0.74 | ALPL (0.53) | KDM4EALDH1A1PKMSMN1; SMN2L3MBTL1 | |
| SCHEMBL1964753 | 0.74 | KDM4E (0.70) | KDM4EALDH1A1PKMSMN1; SMN2L3MBTL1 | |
| SCHEMBL984311 | 0.74 | KDM4E (0.67) | KDM4EALDH1A1PKMSMN1; SMN2L3MBTL1 | |
| SCHEMBL14172837 | 0.73 | KDM4E (0.56) | KDM4EALDH1A1PKMSMN1; SMN2L3MBTL1 | |
| SCHEMBL24984506 | 0.73 | ALPL (0.58) | KDM4EPKMSMN1; SMN2L3MBTL1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |