Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | NNMT | P40261 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL18740622 | 0.81 | HDAC8 (0.48) | HDAC8LMNATSHRBCHEGLA | |
| Bromide SCHEMBL18740639 | 0.77 | HDAC8 (0.45) | HDAC8LMNATSHRBCHEGLA | |
| SCHEMBL9750656 | 0.74 | ALDH1A1 (0.40) | LMNATSHRGLAMAPK1ALDH1A1 | |
| Iodide SCHEMBL18740643 | 0.74 | HDAC8 (0.42) | HDAC8LMNATSHRBCHEGLA | |
| Fluoride Ion SCHEMBL18740632 | 0.74 | HDAC8 (0.42) | HDAC8LMNATSHRBCHEGLA | |
| SCHEMBL13914233 | 0.73 | MAPK1 (0.61) | TSHRGLAMAPK1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL18740634 | 0.71 | HDAC8 (0.39) | HDAC8LMNATSHRBCHEGLA | |
| SCHEMBL25803458 | 0.71 | ALDH1A1 (0.38) | LMNATSHRALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL1940232 | 0.69 | ALDH1A1 (0.61) | HDAC8LMNATSHRMAPK1ALDH1A1 | |
| SCHEMBL16711558 | 0.69 | HDAC8 (0.56) | HDAC8LMNATSHRBCHEGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028601-A | Substituted with an amino thiazole group and a dihydroxy-pyridone group | MEIJI SAIKA KAISHA, LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0289002-A2 | Novel cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA LTD. (JP) | 1988-11-02 | — | — | EP | disclosed |