Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HMGCR | P04035 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518354 | 0.81 | AR (0.48) | ARMEN1KMT2AALDH1A1GAA | |
| SCHEMBL22730883 | 0.80 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL11789135 | 0.79 | POLB (0.51) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL11789226 | 0.78 | MAPT (0.60) | ARMEN1KMT2AALDH1A1GAA | |
| SCHEMBL2884407 | 0.77 | CHRNA7 (0.72) | ALDH1A1MAPTHPGDTSHRTP53 | |
| SCHEMBL1717101 | 0.75 | RECQL (0.55) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL1717801 | 0.75 | MEN1 (0.60) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL1717992 | 0.75 | MEN1 (0.60) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL2882459 | 0.75 | ALDH1A1 (0.46) | ARMEN1KMT2AALDH1A1GAA | |
| SCHEMBL2884107 | 0.75 | ALDH1A1 (0.46) | ARMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055484-A | Anticholesterol and antilipemic agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | disclosed |