Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 5/20 | 0.48 |
| ▸ | SLCO1B1 | Q9Y6L6 | 4/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | RHOC | P08134 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.45 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9272851 | 0.95 | HMGCR (0.46) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL9750852 | 0.87 | HMGCR (0.53) | HMGCRABCB1RAB9AMEN1KMT2A | |
| SCHEMBL9750967 | 0.85 | HMGCR (0.47) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL9750938 | 0.80 | HMGCR (0.51) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL6871693 | 0.78 | HMGCR (0.64) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL9750808 | 0.77 | HMGCR (0.51) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL21637567 | 0.77 | HMGCR (0.60) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL28671880 | 0.76 | ABCB1 (0.53) | ABCB1RAB9ANPC1KDM4EMAPT | |
| SCHEMBL21637575 | 0.76 | HMGCR (0.61) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL23651705 | 0.76 | HMGCR (0.58) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055484-A | Anticholesterol and antilipemic agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | disclosed |