Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 5/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750841 | 0.87 | HMGCR (0.48) | HMGCRABCB1KDM4EALDH1A1MEN1 | |
| SCHEMBL10506117 | 0.83 | ABCB1 (0.65) | HMGCRABCB1KDM4EALDH1A1LMNA | |
| SCHEMBL9272851 | 0.82 | HMGCR (0.46) | HMGCRABCB1TP53GAARAB9A | |
| SCHEMBL9518442 | 0.81 | HMGCR (0.51) | HMGCRABCB1KDM4EALDH1A1TDP1 | |
| SCHEMBL9750837 | 0.80 | HMGCR (0.58) | HMGCRABCB1KDM4EALDH1A1TDP1 | |
| SCHEMBL9751010 | 0.79 | HMGCR (0.49) | HMGCRABCB1KDM4EALDH1A1TDP1 | |
| SCHEMBL8846389 | 0.77 | HMGCR (0.55) | HMGCRABCB1KDM4EALDH1A1TDP1 | |
| SCHEMBL9441634 | 0.76 | MEN1 (0.56) | KDM4EALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL9518353 | 0.76 | HMGCR (0.59) | HMGCRABCB1KDM4EALDH1A1TDP1 | |
| SCHEMBL9750818 | 0.76 | HMGCR (0.59) | HMGCRABCB1KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055484-A | Anticholesterol and antilipemic agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | disclosed |