Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HMGCR | P04035 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28697581 | 0.91 | MEN1 (0.69) | MEN1KMT2AABCB1KDM4EHPGD | |
| SCHEMBL28694855 | 0.90 | ABCB1 (0.74) | MEN1KMT2AABCB1SLC6A4SLC6A3 | |
| SCHEMBL28697576 | 0.88 | ABCB1 (0.60) | MEN1KMT2AABCB1SLC6A4SLC6A3 | |
| SCHEMBL28672791 | 0.87 | MEN1 (0.61) | MEN1KMT2AABCB1KDM4EHPGD | |
| SCHEMBL10506117 | 0.87 | ABCB1 (0.65) | MEN1KMT2AABCB1KDM4EHPGD | |
| SCHEMBL28694853 | 0.84 | MEN1 (0.60) | MEN1KMT2AABCB1KDM4EHPGD | |
| SCHEMBL2880014 | 0.82 | ALDH1A1 (0.61) | MEN1KMT2AABCB1KDM4EHPGD | |
| SCHEMBL28931713 | 0.82 | MEN1 (0.58) | MEN1KMT2AABCB1KDM4EHPGD | |
| SCHEMBL22923862 | 0.80 | MEN1 (0.56) | MEN1KMT2AABCB1SLC6A4SLC6A3 | |
| SCHEMBL28673292 | 0.80 | AR (0.51) | MEN1KMT2ASLC6A4SLC6A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113943242-A | Preparation method of polysubstituted pyrrole compound | 浙江工业大学 | 2022-01-18 | — | — | CN | disclosed |
| US-5055484-A | Anticholesterol and antilipemic agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | disclosed |