Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27751517 | 0.86 | ALDH1A1 (0.41) | KDM4EMAPTTSHRMEN1KMT2A | |
| SCHEMBL12818580 | 0.70 | MAPT (0.38) | KDM4EMAPTTSHRALOX15MEN1 | |
| SCHEMBL18936109 | 0.70 | ALDH1A1 (0.44) | KDM4EMAPTTSHRALOX15MEN1 | |
| SCHEMBL12818577 | 0.69 | CYP1A2 (0.41) | KDM4EMAPTTSHRALOX15MEN1 | |
| SCHEMBL4914625 | 0.68 | — | — | |
| SCHEMBL4921042 | 0.68 | CYP1A2 (0.43) | KDM4EMAPTTSHRALOX15MEN1 | |
| SCHEMBL6429517 | 0.68 | CYP1A2 (0.43) | KDM4EMAPTTSHRALOX15MEN1 | |
| SCHEMBL24175270 | 0.68 | KDM4E (0.48) | KDM4EMAPTTSHRALOX15MEN1 | |
| SCHEMBL10238668 | 0.68 | ALDH1A1 (0.47) | KDM4EMAPTTSHRALOX15MEN1 | |
| SCHEMBL234027 | 0.67 | KDM4E (0.55) | KDM4EMAPTTSHRALOX15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117441732-A | Weeding composition containing 5-phenyl-4, 5-dihydro-isoxazole-3-carboxylic acid ethyl ester | 郑州手性药物研究院有限公司 | 2024-01-26 | — | — | CN | disclosed |
| US-5006515-A | Immunology disorders, antitumor agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |