Sugi Predict

Sugi Predict / Compounds / SCHEMBL975149

SCHEMBL975149

SCHEMBL975149

CC(=O)Oc1ccc(C(C)ON2C(C)(C)CC3(CC2(C)C)OCC(C)(C)CO3)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.34
▸ HSD17B10 Q99714 3/20 0.34
▸ ALDH1A1 P00352 3/20 0.34
▸ HPGD P15428 2/20 0.34
▸ HTT P42858 2/20 0.34
▸ CACNA1B Q00975 2/20 0.34
▸ APBA1 Q02410 2/20 0.34
▸ ATM Q13315 2/20 0.34
▸ TP53 P04637 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ ELANE P08246 3/20 0.34
▸ GLA P06280 1/20 0.34
▸ ESR1 P03372 2/20 0.33
▸ SLC6A3 Q01959 2/20 0.33
▸ ACACB O00763 2/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ ABCB11 O95342 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL976804 0.84 ELANE (0.38) LMNAHSD17B10ALDH1A1HPGDHTT
SCHEMBL976664 0.84 HSD11B1 (0.32) ESR1HSD11B1
SCHEMBL12387763 0.79 ACACB (0.36) ACACB
SCHEMBL13715897 0.79 HCAR2 (0.33) LMNAALDH1A1HTTMAPK1NPSR1
SCHEMBL6470211 0.77 KMT2A (0.30) MAPK1KMT2A
SCHEMBL6088132 0.77 HIF1A (0.41) LMNAALDH1A1HPGDHTTMAPK1
SCHEMBL6087501 0.77 KMT2A (0.48) LMNAALDH1A1ATMMAPK1GLA
SCHEMBL6089141 0.75 KMT2A (0.54) HSD17B10ALDH1A1ATMRAB9AGLA
SCHEMBL6087774 0.75 MAPT (0.41) LMNAALDH1A1MAPK1KDM4EABCB11
SCHEMBL13477328 0.75 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7868171-B2 N-alkoxy-4, 4-dioxy-polyalkyl-piperidines as radical polymerization initiators CIBA SPECIALTY CHEMICALS CORP. (US) 2011-01-11 — — US disclosed
US-7868171-B2 N-alkoxy-4, 4-dioxy-polyalkyl-piperidines as radical polymerization initiators CIBA SPECIALTY CHEMICALS CORP. (US) 2011-01-11 — — US disclosed
US-7868171-B2 N-alkoxy-4, 4-dioxy-polyalkyl-piperidines as radical polymerization initiators CIBA SPECIALTY CHEMICALS CORP. (US) 2011-01-11 — — US disclosed
US-20070173570-A1 N-alkoxy-4, 4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization FUSO FRANCESCO 2007-07-26 — — US disclosed
US-20070173570-A1 N-alkoxy-4, 4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization FUSO FRANCESCO 2007-07-26 — — US disclosed
US-20070173570-A1 N-alkoxy-4, 4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization FUSO FRANCESCO 2007-07-26 — — US disclosed
US-7235663-B2 N-alkoxy-4,4-dioxy-polyalkyl-piperidines as radical polymerization inhibitors CIBA SPECIALTY CHEMICALS CORP. (US) 2007-06-26 — — US disclosed
US-7235663-B2 N-alkoxy-4,4-dioxy-polyalkyl-piperidines as radical polymerization inhibitors CIBA SPECIALTY CHEMICALS CORP. (US) 2007-06-26 — — US disclosed
US-7235663-B2 N-alkoxy-4,4-dioxy-polyalkyl-piperidines as radical polymerization inhibitors CIBA SPECIALTY CHEMICALS CORP. (US) 2007-06-26 — — US disclosed
EP-1341763-B1 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, WITH GLYCIDYL OR ALKYLCARBONYL GROUPS AS FUNCTIONAL INITIATORS FOR CONTROLLED RADICAL POLYMERIZATION CIBA SC HOLDING AG (CH) 2004-06-16 — — EP disclosed
US-20040049043-A1 N-alkoxy-4,4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization CIBA SPECIALTY CHEMICALS CORP. 2004-03-11 — — US disclosed
EP-1341763-A2 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, WITH GLYCIDYL OR ALKYLCARBONYL GROUPS AS FUNCTIONAL INITIATORS FOR CONTROLLED RADICAL POLYMERIZATION Ciba SC Holding AG (CH) 2003-09-10 — — EP disclosed
WO-2002048109-A2 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINES AS RADICAL POLYMERIZATION INITIATORS CIBA SPECIALTY CHEMICLAS HOLDING INC. (CH) 2002-06-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070173570-A1 N-alkoxy-4, 4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization PTGER4, ALKBH3, PIGO LMNA 1104/4885HSD17B10 3431/4885ALDH1A1 737/4885
US-20040049043-A1 N-alkoxy-4,4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization PAOX, ALKBH3, PTGER4 LMNA 1193/4885HSD17B10 3546/4885ALDH1A1 1472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.