Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | PPOX | P50336 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9751619 | 0.93 | TDP1 (0.46) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9768748 | 0.89 | TDP1 (0.54) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10802363 | 0.88 | TDP1 (0.52) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10785506 | 0.87 | SCN9A (0.51) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9751482 | 0.87 | TLR7 (0.41) | TLR7CNR1CNR2TLR8SCN9A | |
| SCHEMBL10359537 | 0.87 | TDP1 (0.52) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10802772 | 0.87 | TDP1 (0.52) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10673745 | 0.86 | TDP1 (0.57) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10748703 | 0.86 | TDP1 (0.57) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10667556 | 0.86 | TDP1 (0.51) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992089-A | Pre- and postemergence | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-12 | — | — | US | disclosed |
| EP-0228788-B1 | HERBICIDAL DERIVATIVES OF SUBSTITUTED BENZOYL-HYDRAZINIUM COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-12-27 | — | — | EP | disclosed |
| EP-0228788-A1 | Herbicidal derivatives of substituted benzoyl-hydrazinium compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-15 | — | — | EP | disclosed |