Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10809942 | 0.88 | RAF1 (0.45) | TLR7SCN9ATLR8BRAFJAK2 | |
| SCHEMBL9751534 | 0.87 | TDP1 (0.52) | TLR7SCN9ACNR1CNR2TLR8 | |
| SCHEMBL10670395 | 0.84 | SCN9A (0.53) | SCN9A | |
| SCHEMBL9751346 | 0.83 | MEN1 (0.48) | TLR7TLR8 | |
| SCHEMBL9751312 | 0.83 | MEN1 (0.41) | TLR7SCN9ATLR8CYP11B1CYP11B2 | |
| SCHEMBL10800743 | 0.81 | L3MBTL1 (0.44) | BRAF | |
| SCHEMBL10806997 | 0.80 | TLR8 (0.38) | TLR7SCN9ATLR8BRAFJAK2 | |
| SCHEMBL10359624 | 0.80 | TLR8 (0.36) | TLR7SCN9ATLR8BRAFJAK2 | |
| SCHEMBL9751382 | 0.79 | GAA (0.41) | TLR7SCN9ACNR1CNR2TLR8 | |
| SCHEMBL10806992 | 0.79 | HTT (0.38) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992089-A | Pre- and postemergence | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-12 | — | — | US | disclosed |
| EP-0228788-B1 | HERBICIDAL DERIVATIVES OF SUBSTITUTED BENZOYL-HYDRAZINIUM COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-12-27 | — | — | EP | disclosed |
| EP-0228788-A1 | Herbicidal derivatives of substituted benzoyl-hydrazinium compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-15 | — | — | EP | disclosed |