SCHEMBL9751592

CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(C)C)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	OPRK1	P41145	2/20	0.45

▸	BACE1	P56817	1/20	0.45

▸	CTSD	P07339	1/20	0.44

▸	PSMB1	P20618	1/20	0.44

▸	PSMB8	P28062	1/20	0.44

▸	PSMB9	P28065	1/20	0.44

▸	PSMB5	P28074	1/20	0.44

▸	PSMB10	P40306	1/20	0.44

▸	PSMB2	P49721	1/20	0.44

▸	GHSR	Q92847	4/20	0.43

▸	C5AR1	P21730	1/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9751589	1.00	OPRK1 (0.45)	OPRK1BACE1CTSDPSMB1PSMB8
SCHEMBL31127562	0.96	SMN1; SMN2 (0.46)	OPRK1BACE1CTSDPSMB1PSMB8
SCHEMBL29904559	0.93	C5AR1 (0.48)	BACE1CTSDC5AR1
SCHEMBL6382012	0.91	SLC15A2 (0.46)	CTSDGHSRC5AR1
SCHEMBL31147166	0.91	F2 (0.48)	OPRK1CTSDGHSR
SCHEMBL9389399	0.91	SLC15A2 (0.46)	CTSDGHSRC5AR1
SCHEMBL9747695	0.91	SLC15A2 (0.46)	CTSDGHSRC5AR1
SCHEMBL10625459	0.90	SLC15A2 (0.45)	CTSDGHSRC5AR1
SCHEMBL29798218	0.90	BACE1 (0.51)	OPRK1BACE1CTSD
SCHEMBL9389401	0.89	C5AR1 (0.48)	BACE1CTSDC5AR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0420914-A1	COSMETIC AND SKIN TREATMENT COMPOSITIONS.	PROCYTE CORP (US)	1991-04-10	—	—	EP	disclosed
WO-1989012441-A1	COSMETIC AND SKIN TREATMENT COMPOSITIONS	PROCYTE CORPORATION (US)	1989-12-28	—	—	WO	disclosed