Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.55 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | RRM1 | P23921 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3293232 | 0.92 | PAOX (0.44) | PAOXGNAI3GNAO1GNAI1SLC6A5 | |
| SCHEMBL545376 | 0.85 | EPHX1 (0.57) | MEN1KMT2AEPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL26598585 | 0.85 | EPHX1 (0.57) | MEN1KMT2AEPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL3298402 | 0.84 | PAOX (0.33) | PAOXGNAI3GNAO1GNAI1MEN1 | |
| SCHEMBL3508069 | 0.81 | PAOX (0.64) | PAOXGNAI3GNAO1GNAI1SLC6A5 | |
| SCHEMBL110911 | 0.81 | PAOX (0.64) | PAOXGNAI3GNAO1GNAI1SLC6A5 | |
| SCHEMBL11524825 | 0.80 | EPHX1 (0.48) | MEN1KMT2AEPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL7210069 | 0.80 | PAOX (0.67) | PAOXGNAI3GNAO1GNAI1SLC6A5 | |
| SCHEMBL8962152 | 0.80 | PAOX (0.67) | PAOXGNAI3GNAO1GNAI1SLC6A5 | |
| SCHEMBL7211245 | 0.80 | PAOX (0.67) | PAOXGNAI3GNAO1GNAI1SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403605-A4 | ELASTASE INHIBITING POLYMERS AND METHODS | UNIV KENTUCKY RES FOUND (US) | 1991-08-21 | — | — | EP | disclosed |
| EP-0403605-A1 | ELASTASE INHIBITING POLYMERS AND METHODS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1990-12-27 | — | — | EP | disclosed |