Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.64 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.42 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RRM1 | P23921 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3508069 | 1.00 | PAOX (0.64) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| Hydrochloric Acid SCHEMBL21772210 | 0.98 | PAOX (0.62) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| Hydrochloric Acid SCHEMBL29050250 | 0.98 | PAOX (0.62) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| SCHEMBL109078 | 0.98 | PAOX (0.61) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| Hydrochloric Acid SCHEMBL21772194 | 0.96 | PAOX (0.59) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| SCHEMBL49567 | 0.92 | PAOX (0.52) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| SCHEMBL28954974 | 0.92 | PAOX (0.52) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| SCHEMBL17307128 | 0.91 | PAOX (0.55) | PAOXGNAI3GNAO1GNAI1HIF1A | |
| SCHEMBL15271425 | 0.91 | PAOX (0.53) | PAOXGNAI3GNAO1GNAI1KDM4E | |
| Phosphoric Acid SCHEMBL9949958 | 0.91 | PAOX (0.53) | PAOXGNAI3GNAO1GNAI1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2063914-B1 | GRAFTED MACROMOLECULAR CONJUGATES OF DOXORUBICIN WITH ANTICANCER ACTIVITY AND METHOD OF THEIR PREPARATION | ZENTIVA KS (CZ) | 2018-12-26 | — | — | EP | disclosed |
| CN-105338947-B | dental material based on monomers containing urea groups | 义获嘉伟瓦登特公司 | 2018-06-01 | — | — | CN | disclosed |
| US-9861557-B2 | Dental materials on the basis of urea group-containing monomers | IVOCLAR VIVADENT AG (LI) | 2018-01-09 | — | — | US | disclosed |
| US-9861557-B2 | Dental materials on the basis of urea group-containing monomers | IVOCLAR VIVADENT AG (LI) | 2018-01-09 | — | — | US | disclosed |
| EP-2823801-B1 | Dental materials on the basis of monomers containing urea groups | IVOCLAR VIVADENT AG (LI) | 2017-04-19 | — | — | EP | disclosed |
| EP-2823801-B1 | Dental materials on the basis of monomers containing urea groups | IVOCLAR VIVADENT AG (LI) | 2017-04-19 | — | — | EP | disclosed |
| US-20160151249-A1 | DENTAL MATERIALS ON THE BASIS OF UREA GROUP-CONTAINING MONOMERS | IVOCLAR VIVADENT AG (LI) | 2016-06-02 | — | — | US | disclosed |
| US-20160151249-A1 | DENTAL MATERIALS ON THE BASIS OF UREA GROUP-CONTAINING MONOMERS | IVOCLAR VIVADENT AG (LI) | 2016-06-02 | — | — | US | disclosed |
| US-20160151249-A1 | DENTAL MATERIALS ON THE BASIS OF UREA GROUP-CONTAINING MONOMERS | IVOCLAR VIVADENT AG (LI) | 2016-06-02 | — | — | US | disclosed |
| CN-105338947-A | Dental material based on monomers containing urea groups | IVOCLAR VIVADENT AG | 2016-02-17 | — | — | CN | disclosed |
| US-8722931-B2 | Compound and method for preparing the same | FUJIFILM CORPORATION (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8722931-B2 | Compound and method for preparing the same | FUJIFILM CORPORATION (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8603990-B2 | Grafted macromolecular conjugates of doxorubicin with anticancer activity and method of their preparation | ZENTIVA K.S. (CS) | 2013-12-10 | — | — | US | disclosed |
| US-20120165572-A1 | NOVEL COMPOUND AND METHOD FOR PREPARING THE SAME | FUJIFILM CORPORATION (JP) | 2012-06-28 | — | — | US | disclosed |
| EP-2424491-A2 | FILM FORMER IN HAIR DYES | Henkel AG & Co. KGaA (DE) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010124897-A2 | FILM FORMER IN HAIR DYES | HENKEL AG & CO. KGAA (DE) | 2010-11-04 | — | — | WO | disclosed |
| US-20090306004-A1 | GRAFTED MACROMOLECULAR CONJUGATES OF DOXORUBICIN WITH ANTICANCER ACTIVITY AND METHOD OF THEIR PREPARATION | ZENTIVA K.S. (CZ) | 2009-12-10 | — | — | US | disclosed |
| US-20090264551-A1 | Photocurable fixture for orthopedic surgery background of the invention | ALCARE CO., LTD. | 2009-10-22 | — | — | US | disclosed |
| EP-2063914-A1 | GRAFTED MACROMOLECULAR CONJUGATES OF DOXORUBICIN WITH ANTICANCER ACTIVITY AND METHOD OF THEIR PREPARATION | Zentiva, k.s. (CZ) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008034391-A1 | GRAFTED MACROMOLECULAR CONJUGATES OF DOXORUBICIN WITH ANTICANCER ACTIVITY AND METHOD OF THEIR PREPARATION | ZENTIVA, A.S. (CZ) | 2008-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306004-A1 | GRAFTED MACROMOLECULAR CONJUGATES OF DOXORUBICIN WITH ANTICANCER ACTIVITY AND METHOD OF THEIR PREPARATION | DNPEP, HDGF, LNPEP | PAOX 3958/4885GNAI3 3501/4885GNAO1 2589/4885 |
| US-20120165572-A1 | NOVEL COMPOUND AND METHOD FOR PREPARING THE SAME | ADCY1, ADCY2, ADCY5 | PAOX 2295/4885GNAI3 548/4885GNAO1 314/4885 |
| US-20160151249-A1 | DENTAL MATERIALS ON THE BASIS OF UREA GROUP-CONTAINING MONOMERS | UFM1, SLC14A1, USO1 | PAOX 2235/4885GNAI3 3847/4885GNAO1 2425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.