Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL576123 | 0.82 | TSHR (0.35) | — | |
| SCHEMBL576941 | 0.74 | HTR7 (0.43) | PTPN1 | |
| SCHEMBL9683864 | 0.71 | HSD17B10 (0.33) | HSD17B10 | |
| SCHEMBL17972368 | 0.71 | HTR7 (0.33) | LPAR1 | |
| SCHEMBL16186315 | 0.71 | HTR7 (0.33) | LPAR1 | |
| SCHEMBL980842 | 0.68 | AKR1B1 (0.33) | — | |
| SCHEMBL981439 | 0.68 | HTR7 (0.30) | — | |
| SCHEMBL576526 | 0.68 | HTR7 (0.48) | — | |
| SCHEMBL576487 | 0.68 | AKR1B1 (0.33) | CYP1A2LPAR1 | |
| SCHEMBL979122 | 0.68 | AKR1B1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417203-A1 | PROCESS FOR THE PREPARATION OF GAMMA AND DELTA LACTONES. | BASF CORP (US) | 1991-03-20 | — | — | EP | disclosed |
| WO-1989012104-A1 | PROCESS FOR THE PREPARATION OF GAMMA AND DELTA LACTONES | BASF CORPORATION (US) | 1989-12-14 | — | — | WO | disclosed |