Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 6/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | METAP1 | P53582 | 2/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAPDH | P04406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10472310 | 0.93 | POLB (0.47) | POLBCASP6AKR1B1MAOBCYP19A1 | |
| SCHEMBL11805315 | 0.87 | POLB (0.46) | POLBCASP6AKR1B1MAOBCREBBP | |
| SCHEMBL1292089 | 0.82 | POLB (0.56) | POLBCASP6AKR1B1MAOBCREBBP | |
| SCHEMBL26107947 | 0.80 | MAOB (0.38) | AKR1B1MAOBCREBBPPTGS2TP53 | |
| SCHEMBL10470237 | 0.77 | RAB9A (0.39) | MAOBCA12CA9LMNAMEN1 | |
| SCHEMBL11174379 | 0.77 | SMN1; SMN2 (0.45) | POLBAKR1B1MAOBCREBBPTP53 | |
| SCHEMBL9327125 | 0.75 | POLB (0.56) | POLBCASP6MAOBCYP19A1MAPT | |
| SCHEMBL10511106 | 0.74 | PPARG (0.43) | HPGDKMT2A | |
| SCHEMBL10470447 | 0.74 | POLB (0.47) | POLBCASP6AKR1B1MAOBTDP1 | |
| SCHEMBL10472053 | 0.74 | POLB (0.48) | POLBCASP6MAOBCYP19A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0439607-A4 | NOVEL GLYOXYLATES AND HERBICIDAL AND PLANT GROWTH REGULANT ACTIVITY OF GLYOXYLATES | — | 1991-12-04 | — | — | EP | disclosed |
| EP-0439607-A1 | NOVEL GLYOXYLATES AND HERBICIDAL AND PLANT GROWTH REGULANT ACTIVITY OF GLYOXYLATES | ISK BIOSCIENCES CORPORATION (US) | 1991-08-07 | — | — | EP | disclosed |
| WO-1991000009-A1 | NOVEL GLYOXYLATES AND HERBICIDAL AND PLANT GROWTH REGULANT ACTIVITY OF GLYOXYLATES | FERMENTA ASC CORPORATION (US) | 1991-01-10 | — | — | WO | disclosed |