Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10471437 | 0.86 | POLB (0.43) | POLBCASP6NISCHL3MBTL1MAOA | |
| SCHEMBL9752013 | 0.85 | KMT2A (0.38) | NISCHL3MBTL1MAOAMAOBALDH1A1 | |
| SCHEMBL9327125 | 0.85 | POLB (0.56) | POLBCASP6NISCHMAOAMAOB | |
| SCHEMBL10473088 | 0.84 | POLB (0.44) | POLBCASP6NISCHL3MBTL1MAOA | |
| SCHEMBL10471441 | 0.84 | POLB (0.44) | POLBCASP6NISCHMAOAMAOB | |
| SCHEMBL10470737 | 0.84 | POLB (0.41) | POLBCASP6NISCHMAOAMAOB | |
| Hydrochloric Acid SCHEMBL9751989 | 0.83 | POLB (0.55) | POLBCASP6NISCHMAOAMAOB | |
| SCHEMBL10472308 | 0.83 | POLB (0.43) | POLBCASP6NISCHMAOAMAOB | |
| SCHEMBL10470236 | 0.83 | POLB (0.43) | POLBCASP6NISCHL3MBTL1MAOA | |
| SCHEMBL10470216 | 0.83 | KDM4E (0.41) | POLBCASP6NISCHL3MBTL1ACSL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4979978-A | Herbicidal 12H-dibenzo[d,g][1,3]dioxocin-6-carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1990-12-25 | — | — | US | claimed |
| EP-0439607-A4 | NOVEL GLYOXYLATES AND HERBICIDAL AND PLANT GROWTH REGULANT ACTIVITY OF GLYOXYLATES | — | 1991-12-04 | — | — | EP | disclosed |
| EP-0439607-A1 | NOVEL GLYOXYLATES AND HERBICIDAL AND PLANT GROWTH REGULANT ACTIVITY OF GLYOXYLATES | ISK BIOSCIENCES CORPORATION (US) | 1991-08-07 | — | — | EP | disclosed |
| WO-1991000009-A1 | NOVEL GLYOXYLATES AND HERBICIDAL AND PLANT GROWTH REGULANT ACTIVITY OF GLYOXYLATES | FERMENTA ASC CORPORATION (US) | 1991-01-10 | — | — | WO | disclosed |
| US-4979978-A | Herbicidal 12H-dibenzo[d,g][1,3]dioxocin-6-carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1990-12-25 | — | — | US | disclosed |
| US-4976770-A | POSTEMERGENCE, PREEMERGENCE HERBICIDES | FERMENTA ASC CORPORATION (US) | 1990-12-11 | — | — | US | disclosed |