SCHEMBL9752013

SCHEMBL9752013

COC(=O)C1Oc2ccccc2Cc2cccc(C)c2O1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.38
MEN1 O00255 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
ALDH1A1 P00352 1/20 0.35
MAPK1 P28482 1/20 0.35
NISCH Q9Y2I1 1/20 0.34
GABRA1 P14867 2/20 0.34
GABRB2 P47870 2/20 0.34
NPC1 O15118 1/20 0.34
TP53 P04637 2/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
HTT P42858 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC5 Q9UQL6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9752010 0.92 L3MBTL1 (0.41) KMT2AMEN1L3MBTL1ALDH1A1MAPK1
SCHEMBL10471599 0.89 L3MBTL1 (0.36) KMT2AMEN1L3MBTL1ALDH1A1MAPK1
SCHEMBL9752005 0.88 MAOA (0.42) KMT2AL3MBTL1ALDH1A1MAPK1NISCH
SCHEMBL10472315 0.87 HDAC4 (0.35) KMT2AMEN1L3MBTL1ALDH1A1NISCH
SCHEMBL10470798 0.87 CA12 (0.34) KMT2AMEN1L3MBTL1ALDH1A1NISCH
SCHEMBL10470238 0.86 TDP1 (0.38) L3MBTL1ALDH1A1NISCHGABRA1GABRB2
SCHEMBL10471566 0.86 CTNNB1 (0.39) KMT2AMEN1L3MBTL1ALDH1A1MAPK1
SCHEMBL9751997 0.85 POLB (0.43) L3MBTL1ALDH1A1MAPK1NISCHMAOA
SCHEMBL10472007 0.85 HSD17B10 (0.35) KMT2AMEN1L3MBTL1ALDH1A1MAPK1
SCHEMBL9752006 0.84 ATM (0.33) KMT2AMEN1L3MBTL1ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0439607-A4 NOVEL GLYOXYLATES AND HERBICIDAL AND PLANT GROWTH REGULANT ACTIVITY OF GLYOXYLATES 1991-12-04 EP disclosed
EP-0439607-A1 NOVEL GLYOXYLATES AND HERBICIDAL AND PLANT GROWTH REGULANT ACTIVITY OF GLYOXYLATES ISK BIOSCIENCES CORPORATION (US) 1991-08-07 EP disclosed
WO-1991000009-A1 NOVEL GLYOXYLATES AND HERBICIDAL AND PLANT GROWTH REGULANT ACTIVITY OF GLYOXYLATES FERMENTA ASC CORPORATION (US) 1991-01-10 WO disclosed
US-4979978-A Herbicidal 12H-dibenzo[d,g][1,3]dioxocin-6-carboxylic acids THE DOW CHEMICAL COMPANY (US) 1990-12-25 US disclosed
US-4976770-A POSTEMERGENCE, PREEMERGENCE HERBICIDES FERMENTA ASC CORPORATION (US) 1990-12-11 US disclosed