Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265890 | 0.92 | MGAM (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL3426953 | 0.86 | KMT2A (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL27539379 | 0.86 | MGAM (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL7767241 | 0.86 | MGAM (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL1823767 | 0.83 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL4755497 | 0.83 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL1853675 | 0.82 | MGAM (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| Succinic Acid Diethyl Ester SCHEMBL27962258 | 0.81 | CYP1A2 (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL30764119 | 0.80 | CYP1A2 (0.38) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL454062 | 0.80 | TDP1 (0.58) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103421849-B | A kind of compound with antibacterial activity and preparation method thereof | 上海医药工业研究院 | 2016-06-22 | — | — | CN | disclosed |
| CN-103421084-A | Antibacterial compound | SHANGHAI INST PHARM INDUSTRY | 2013-12-04 | — | — | CN | disclosed |
| CN-103421849-A | Compound with antibacterial activity and preparation method thereof | SHANGHAI INST PHARM INDUSTRY | 2013-12-04 | — | — | CN | disclosed |
| EP-0449884-A4 | DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS | — | 1991-10-30 | — | — | EP | disclosed |
| EP-0449884-A1 | DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS | ABBOTT LABORATORIES (US) | 1991-10-09 | — | — | EP | disclosed |
| WO-1990006937-A1 | DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS | ABBOTT LABORATORIES (US) | 1990-06-28 | — | — | WO | disclosed |
| US-4801697-A | BRONCHODILATOR, MUSCLE RELAXANT, HORMONE EXCRETION STIMULANT | TOYO JOZO KABUSHIKI KAISHA (JP) | 1989-01-31 | — | — | US | disclosed |
| US-4199355-A | BALLASTED CHROMOGENS | EASTMAN KODAK COMPANY (US) | 1980-04-22 | — | — | US | disclosed |
| US-4152524-A | BRONCHODILATORS, HYPOTENSIVE | AMERICAN CYANAMID COMPANY (US) | 1979-05-01 | — | — | US | disclosed |
| US-4076947-A | BRONCHODILATORS, HYPOTENSIVE AGENTS, ANTIULCER AGENTS | AMERICAN CYANAMID COMPANY (US) | 1978-02-28 | — | — | US | disclosed |
| US-4045577-A | 15-PROPIONYLOXY-9-OXO-5,13 PROSTADIENOIC ACID, ANTIHYPERTENSIVE AGENTS | ALZA CORPORATION (US) | 1977-08-30 | — | — | US | disclosed |
| US-3992413-A | Intermediates in the synthesis of prostaglandins | MERCK & CO., INC. (US) | 1976-11-16 | — | — | US | disclosed |