SCHEMBL7767241

SCHEMBL7767241

CCOC(=O)CC(CC(=O)O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.44
GAA P10253 1/20 0.44
SI P14410 1/20 0.44
MGAM2 Q2M2H8 1/20 0.44
FOLH1 Q04609 2/20 0.43
ALDH1A1 P00352 6/20 0.41
TRPA1 O75762 1/20 0.41
TSHR P16473 2/20 0.39
TDP1 Q9NUW8 3/20 0.39
CYP3A4 P08684 2/20 0.39
ALOX15 P16050 2/20 0.39
CHRM1 P11229 2/20 0.38
AKR1A1 P14550 1/20 0.38
CHRM3 P20309 1/20 0.38
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
ADRA1A P35348 1/20 0.38
HRH1 P35367 1/20 0.38
DRD3 P35462 1/20 0.38
SLC6A3 Q01959 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6265890 0.94 MGAM (0.50) MGAMGAASIMGAM2ALDH1A1
SCHEMBL28071880 0.88 KMT2A (0.49) MGAMGAASIMGAM2ALDH1A1
SCHEMBL9752041 0.86 MGAM (0.43) MGAMGAASIMGAM2ALDH1A1
SCHEMBL1823767 0.85 MGAM (0.46) MGAMGAASIMGAM2ALDH1A1
SCHEMBL4755497 0.85 MGAM (0.46) MGAMGAASIMGAM2ALDH1A1
SCHEMBL1853675 0.83 MGAM (0.44) MGAMGAASIMGAM2ALDH1A1
SCHEMBL454062 0.82 TDP1 (0.58) MGAMGAASIMGAM2FOLH1
SCHEMBL4831221 0.81 GAA (0.40) MGAMGAASIMGAM2ALDH1A1
SCHEMBL8047058 0.80 SLC1A3 (0.46) MGAMGAASIMGAM2ALDH1A1
SCHEMBL2637671 0.80 SLC1A3 (0.46) MGAMGAASIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1117677-A1 LIGAND PRESENTING ASSEMBLY (LPA), METHOD OF PREPARATION AND USES THEREOF Statens Serum Institut (DK) 2001-07-25 EP claimed
WO-2000018791-A1 LIGAND PRESENTING ASSEMBLY (LPA), METHOD OF PREPARATION AND USES THEREOF STATENS SERUM INSTITUT (DK) 2000-04-06 WO claimed
EP-0248932-B1 PROCESS FOR PREPARING POLYAMIDES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-01-09 EP disclosed
EP-0177793-B1 PROCESS FOR PREPARING POLYAMIDES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1990-11-28 EP disclosed
US-4754016-A Process for preparing polyamide with organic phosphine/organic disulfide mixture condensing agent ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-06-28 US disclosed
EP-0248932-A1 Process for preparing polyamides Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-12-16 EP disclosed
US-4645823-A CORROSION RESISTANCE; NONTOXIC ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1987-02-24 US disclosed
EP-0177793-A2 Process for preparing polyamides Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-04-16 EP disclosed