SCHEMBL9752044

SCHEMBL9752044

O=C(ON1C(=O)CCC1=O)c1cc2cc(Cl)ccc2[nH]1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
F7 P08709 1/20 0.55
F3 P13726 1/20 0.55
HRH4 Q9H3N8 9/20 0.52
HRH3 Q9Y5N1 4/20 0.52
HRH1 P35367 1/20 0.50
FLT3 P36888 1/20 0.49
KMT2A Q03164 5/20 0.49
MEN1 O00255 3/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
RXFP1 Q9HBX9 1/20 0.48
PYGL P06737 1/20 0.46
POLB P06746 1/20 0.45
SMYD3 Q9H7B4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29440256 0.82 KDM4E (0.54) HRH4HRH3FLT3NPC1RAB9A
SCHEMBL9802132 0.82 KDM4E (0.54) HRH4HRH3FLT3NPC1RAB9A
SCHEMBL25437750 0.80 HRH4 (0.49) HRH4
SCHEMBL31219213 0.76 F7 (0.66) F7F3HRH4HRH3HRH1
SCHEMBL3963537 0.76 F7 (0.66) F7F3HRH4HRH3HRH1
SCHEMBL10381849 0.76 KDM4E (0.66) FLT3KMT2AMEN1
SCHEMBL31264281 0.72 ALOX15 (0.79) F7F3HRH3FLT3KMT2A
SCHEMBL26213276 0.72 KDM4E (0.67) F7F3HRH4HRH3HRH1
SCHEMBL42366 0.72 ALOX15 (0.79) F7F3HRH3FLT3KMT2A
SCHEMBL4666737 0.72 F7 (0.60) F7F3HRH4HRH3HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023107597-A2 BICYCLIC HETEROAROMATIC AMIDE COMPOUNDS AND USES THEREOF Kineta, Inc. (US) 2023-06-15 WO disclosed
EP-0449884-A4 DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS 1991-10-30 EP disclosed
EP-0449884-A1 DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS ABBOTT LABORATORIES (US) 1991-10-09 EP disclosed
WO-1990006937-A1 DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS ABBOTT LABORATORIES (US) 1990-06-28 WO disclosed