SCHEMBL9752189

SCHEMBL9752189

C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=B[O-]

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.35
CYP2D6 P10635 2/20 0.33
TDP1 Q9NUW8 1/20 0.32
ESR1 P03372 1/20 0.32
ALDH1A1 P00352 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CYP1A2 P05177 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
PTGS2 P35354 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
XBP1 P17861 1/20 0.30
ATM Q13315 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
TAAR1 Q96RJ0 2/20 0.30
MAOA P21397 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7237367 0.84 HIF1A (0.41) HIF1ACYP2D6TDP1ALDH1A1L3MBTL1
SCHEMBL29371667 0.84 HIF1A (0.45) HIF1ACYP2D6TDP1ALDH1A1L3MBTL1
Bromide SCHEMBL29712281 0.81 HIF1A (0.43) HIF1ACYP2D6TDP1ALDH1A1L3MBTL1
SCHEMBL10416287 0.81 HIF1A (0.43) HIF1ACYP2D6TDP1ALDH1A1L3MBTL1
Benzene SCHEMBL27680989 0.81 HIF1A (0.43) HIF1ACYP2D6TDP1ALDH1A1L3MBTL1
Iodide SCHEMBL29937613 0.81 HIF1A (0.43) HIF1ACYP2D6TDP1ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL114803 0.81 HIF1A (0.43) HIF1ACYP2D6TDP1ALDH1A1L3MBTL1
Fluoride Ion SCHEMBL4615710 0.81 HIF1A (0.43) HIF1ACYP2D6TDP1ALDH1A1L3MBTL1
Bromide SCHEMBL3076 0.81 HIF1A (0.43) HIF1ACYP2D6TDP1ALDH1A1L3MBTL1
Water SCHEMBL2821350 0.81 HIF1A (0.43) HIF1ACYP2D6TDP1ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991001391-A1 PRODUCTION OF METAL BOROHYDRIDES AND ORGANIC ONIUM BOROHYDRIDES SOUTHWESTERN ANALYTICAL CHEMICALS, INC. (US) 1991-02-07 WO disclosed
US-4931154-A Production of metal borohydrides and organic onium borohydrides SOUTHWESTERN ANALYTICAL CHEMICALS, INC. (US) 1990-06-05 US disclosed