Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.37 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27680989 | 1.00 | HIF1A (0.43) | HIF1ATDP1LMNATSHRALOX12 | |
| Hydrochloric Acid SCHEMBL29105928 | 0.97 | HIF1A (0.41) | HIF1ATDP1LMNATSHRALOX12 | |
| SCHEMBL29371667 | 0.97 | HIF1A (0.45) | HIF1ATDP1LMNATSHRALOX12 | |
| Iodide SCHEMBL42631 | 0.93 | HIF1A (0.43) | HIF1ATDP1LMNATSHRALOX12 | |
| SCHEMBL10416287 | 0.93 | HIF1A (0.43) | HIF1ATDP1LMNATSHRALOX12 | |
| Iodide SCHEMBL29937613 | 0.93 | HIF1A (0.43) | HIF1ATDP1LMNATSHRALOX12 | |
| Bromide SCHEMBL3076 | 0.93 | HIF1A (0.43) | HIF1ATDP1LMNATSHRALOX12 | |
| Fluoride Ion SCHEMBL4615710 | 0.93 | HIF1A (0.43) | HIF1ATDP1LMNATSHRALOX12 | |
| Water SCHEMBL2821350 | 0.93 | HIF1A (0.43) | HIF1ATDP1LMNATSHRALOX12 | |
| Bromide SCHEMBL29712281 | 0.93 | HIF1A (0.43) | HIF1ATDP1LMNATSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122010689-A | Preparation method of cycloparaffin | 浙江清华长三角研究院 | 2026-05-12 | — | — | CN | claimed |
| US-20260109730-A1 | Process For The Preparation Of (3Beta,24S)-25,25,25-Trifluoro-3-Methyl-26,27-Dinorergost-5-ene-3,24-Diol | IND CHIMICA SRL (IT) | 2026-04-23 | — | — | US | claimed |
| EP-4713317-A1 | A PROCESS FOR PURIFICATION OF ETHOFUMESATE | Adama Agan Ltd. (IL) | 2026-03-25 | — | — | EP | claimed |
| CN-120040438-A | Isoxazole antiparasitic agents Synthesis method of medicine lotirana | 华南农业大学 | 2025-05-27 | — | — | CN | claimed |
| CN-114878542-B | Be used for simultaneously detecting intracellular Cu of mitochondria+And Cu2+Surface-enhanced Raman spectrum probe of (2), preparation and application thereof | 华东师范大学 | 2025-02-11 | — | — | CN | claimed |
| CN-119350290-A | Method for preparing 1, 4-dioxane-2-ketone from ethylene carbonate | 青岛科技大学 | 2025-01-24 | — | — | CN | claimed |
| WO-2024236570-A1 | A PROCESS FOR PURIFICATION OF ETHOFUMESATE | ADAMA AGAN LTD. (IL) | 2024-11-21 | — | — | WO | claimed |
| US-20240287009-A1 | AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME | INFINEUM INTERNATIONAL LIMITED (GB) | 2024-08-29 | — | — | US | claimed |
| EP-4410772-A2 | AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME | Infineum International Limited (GB) | 2024-08-07 | — | — | EP | claimed |
| CN-118440229-A | Amine functional monomers and methods of making the same | 英菲诺姆国际有限公司 | 2024-08-06 | — | — | CN | claimed |
| EP-0667346-A2 | Azole antifungal agents, process for the preparation there of and intermediates | Eisai Co., Ltd. (JP) | 1995-08-16 | — | — | EP | claimed |
| US-RE34761-E | Process for the preparation of trichloroethylene | WACKER-CHEMIE GMBH (DE) | 1994-10-18 | — | — | US | claimed |
| EP-0523553-B1 | Process for the hydrogenation of chloromethanes | WACKER CHEMIE GMBH (DE) | 1993-11-03 | — | — | EP | claimed |
| EP-0432636-B1 | Process for preparing trichloroethylene | WACKER CHEMIE GMBH (DE) | 1993-10-27 | — | — | EP | claimed |
| US-5233106-A | PROCESS FOR THE HYDROGENATION OF CHLOROMETHANES | WACKER-CHEMIE GMBH (DE) | 1993-08-03 | — | — | US | claimed |
| EP-0523553-A1 | Process for the hydrogenation of chloromethanes | WACKER-CHEMIE GMBH (DE) | 1993-01-20 | — | — | EP | claimed |
| US-5091603-A | Reacting perchloroethylene and hydrogen using active charcoal catalyst support impregnated with copper, modium or palladium metals or compounds | WACKER-CHEMIE GMBH (DE) | 1992-02-25 | — | — | US | claimed |
| EP-0432636-A1 | Process for preparing trichloroethylene | WACKER-CHEMIE GMBH (DE) | 1991-06-19 | — | — | EP | claimed |
| US-4831166-A | REACTING ALKYLENE OXIDE WITH ACYLACETATE USING IONIC HALIDE CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 1989-05-16 | — | — | US | claimed |
| US-4810808-A | Process for preparing polyglycidyl compounds | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-03-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240287009-A1 | AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME | AMD1, HNMT, MAT1A | ACHE 703/4885SLC6A2 1973/4885SLC6A3 2219/4885 |
| US-20260109730-A1 | Process For The Preparation Of (3Beta,24S)-25,25,25-Trifluoro-3-Methyl-26,27-Dinorergost-5-ene-3,24-Diol | HSD17B7, CYP11B1, CYP11B2 | ACHE 1044/4885SLC6A2 3778/4885SLC6A3 2151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.