Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | MGMT | P16455 | 2/20 | 0.37 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | ADCY5 | O95622 | 6/20 | 0.36 |
| ▸ | MPO | P05164 | 2/20 | 0.34 |
| ▸ | TPO | P07202 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | EPX | P11678 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752237 | 1.00 | ABCB1 (0.43) | ABCB1NR1I2ALBPDE4DBCHE | |
| SCHEMBL9752215 | 1.00 | ABCB1 (0.43) | ABCB1NR1I2ALBPDE4DBCHE | |
| SCHEMBL9752225 | 0.85 | ABCB1 (0.48) | ABCB1NR1I2ALBPDE4DBCHE | |
| SCHEMBL9752224 | 0.85 | ABCB1 (0.48) | ABCB1NR1I2ALBPDE4DBCHE | |
| SCHEMBL23391245 | 0.83 | NR1I2 (0.48) | ABCB1NR1I2ALBPDE4DBCHE | |
| SCHEMBL28529107 | 0.83 | NR1I2 (0.48) | ABCB1NR1I2ALBPDE4DBCHE | |
| SCHEMBL23391347 | 0.82 | NR1I2 (0.59) | ABCB1NR1I2ALBPDE4DBCHE | |
| SCHEMBL9752163 | 0.81 | MGMT (0.39) | MGMTPDE2A | |
| SCHEMBL23408482 | 0.81 | NR1I2 (0.50) | ABCB1NR1I2ALBPDE4DBCHE | |
| SCHEMBL23391344 | 0.80 | ABCB1 (0.39) | ABCB1NR1I2ALBPDE4DBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991001318-A1 | SYNTHESIS OF CYCLOPENTENE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1991-02-07 | — | — | WO | disclosed |