Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 2/20 | 0.39 |
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | NAE1 | Q13564 | 3/20 | 0.38 |
| ▸ | UBA3 | Q8TBC4 | 3/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | AHCY | P23526 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752227 | 0.87 | MGMT (0.34) | MGMTPDE2AHSPA5NT5E | |
| SCHEMBL9752226 | 0.87 | MGMT (0.34) | MGMTPDE2AHSPA5NT5E | |
| SCHEMBL9752212 | 0.86 | PDE2A (0.49) | PDE2ANAE1UBA3NT5EADORA2A | |
| SCHEMBL9752215 | 0.81 | ABCB1 (0.43) | MGMTPDE2A | |
| SCHEMBL9752214 | 0.81 | ABCB1 (0.43) | MGMTPDE2A | |
| SCHEMBL9752237 | 0.81 | ABCB1 (0.43) | MGMTPDE2A | |
| SCHEMBL9366104 | 0.78 | AHCY (0.48) | MGMTPDE2ANT5EADORA2AADORA2B | |
| SCHEMBL9366097 | 0.78 | AHCY (0.48) | MGMTPDE2ANT5EADORA2AADORA2B | |
| SCHEMBL9752219 | 0.77 | MGMT (0.40) | MGMTPDE2AHSPA5NT5EADORA2A | |
| SCHEMBL9752216 | 0.77 | MGMT (0.40) | MGMTPDE2AHSPA5NT5EADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991001318-A1 | SYNTHESIS OF CYCLOPENTENE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1991-02-07 | — | — | WO | disclosed |