Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 3/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.38 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752280 | 1.00 | ACE (0.52) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL930999 | 0.85 | ACE (0.72) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL30663369 | 0.83 | ACE (0.50) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL9052241 | 0.83 | ACE (0.50) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL30885617 | 0.83 | ACE (0.50) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL929011 | 0.83 | ACE (0.55) | ACE | |
| SCHEMBL9053775 | 0.83 | ACE (0.50) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL929013 | 0.83 | ACE (0.55) | ACE | |
| SCHEMBL9052239 | 0.83 | ACE (0.50) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL8726316 | 0.83 | ACE (0.55) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991010421-A1 | USE OF N-ACYL DERIVATIVES OF HOMOCYSTEINE TO MODIFY THE STRUCTURE OF KERATIN AND COSMETIC COMPOSITIONS CONTAINING THESE DERIVATIVES | RECKITT & COLMAN (FR) | 1991-07-25 | — | — | WO | disclosed |