Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Phenylmethanesulfonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 3/20 | 0.45 |
| ▸ | NOS1 | P29475 | 2/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylmethanesulfonic Acid SCHEMBL127384 | 0.89 | CA2 (0.58) | CA1CA2CA5ACA9PRSS1 | |
| Phenylmethanesulfonic Acid SCHEMBL1749 | 0.89 | CA2 (0.58) | CA1CA2CA5ACA9PRSS1 | |
| Phenylmethanesulfonic Acid SCHEMBL28294303 | 0.89 | CA2 (0.58) | CA1CA2CA5ACA9PRSS1 | |
| Phenylmethanesulfonic Acid SCHEMBL30217949 | 0.89 | CA2 (0.58) | CA1CA2CA5ACA9PRSS1 | |
| Phenylmethanesulfonic Acid SCHEMBL7148383 | 0.89 | F2 (0.52) | CA1CA2CA5ACA9PRSS1 | |
| Phenylmethanesulfonic Acid SCHEMBL11870010 | 0.87 | CA2 (0.58) | CA1CA2CA5ACA9PRSS1 | |
| Phenylmethanesulfonic Acid SCHEMBL589697 | 0.87 | CA2 (0.56) | CA1CA2CA5ACA9PRSS1 | |
| Phenylmethanesulfonic Acid SCHEMBL1739278 | 0.87 | CA2 (0.56) | CA1CA2CA5ACA9PRSS1 | |
| Phenylmethanesulfonic Acid SCHEMBL1073102 | 0.87 | CA2 (0.56) | CA1CA2CA5ACA9PRSS1 | |
| Phenylmethanesulfonic Acid SCHEMBL21811372 | 0.87 | CA2 (0.56) | CA1CA2CA5ACA9PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338923-B1 | Polyurethane with a biocidal polyuric material as comonomer | OBERWALDER SEBASTIAN (DE) | 2017-10-18 | — | — | EP | claimed |
| EP-2338342-A1 | Polyuric material with biocidal characteristics | Oberwalder, Sebastian (DE) | 2011-06-29 | — | — | EP | claimed |
| EP-2338923-A1 | Polyurethane with a biocidal polyuric material as comonomer | Oberwalder, Sebastian (DE) | 2011-06-29 | — | — | EP | claimed |
| EP-2338923-B1 | Polyurethane with a biocidal polyuric material as comonomer | OBERWALDER SEBASTIAN (DE) | 2017-10-18 | — | — | EP | disclosed |
| EP-2338342-A1 | Polyuric material with biocidal characteristics | Oberwalder, Sebastian (DE) | 2011-06-29 | — | — | EP | disclosed |
| EP-2338923-A1 | Polyurethane with a biocidal polyuric material as comonomer | Oberwalder, Sebastian (DE) | 2011-06-29 | — | — | EP | disclosed |
| WO-1991000329-A1 | PROCESS FOR THE TREATMENT OF USED OIL | GEUT AG GESELLSCHAFT FÜR ENERGIE- UND UMWELTTECHNIK (CH) | 1991-01-10 | — | — | WO | disclosed |