SCHEMBL97524

SCHEMBL97524

COc1ccccc1[C]=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.55
CA2 P00918 4/20 0.55
CA7 P43166 3/20 0.55
CA9 Q16790 3/20 0.55
CA12 O43570 2/20 0.55
CA14 Q9ULX7 2/20 0.55
CA4 P22748 1/20 0.55
ALDH1A1 P00352 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
ADRA2B P18089 1/20 0.44
PTGS1 P23219 1/20 0.44
MAPK1 P28482 1/20 0.43
HTT P42858 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
GRM5 P41594 1/20 0.42
FFAR1 O14842 1/20 0.41
ENPP2 Q13822 1/20 0.41
POLB P06746 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL263687 0.80 SMN1; SMN2 (0.45) CA1CA2CA7CA9CA12
SCHEMBL11511313 0.80 CA1 (0.42) CA1CA2CA7CA9CA12
SCHEMBL6208988 0.80 CA1 (0.45) CA1CA2CA7CA9CA12
SCHEMBL1495183 0.80 POLB (0.35) CA1CA2CA7CA9CA12
SCHEMBL9166410 0.80 GAA (0.39) CA1CA2CA7CA9CA12
SCHEMBL30022461 0.80 CA1 (0.60) CA1CA2CA7CA9CA12
SCHEMBL4214499 0.80 CA1 (0.60) CA1CA2CA7CA9CA12
SCHEMBL9467799 0.80 TOP1 (0.49) CA1CA2CA7CA9CA12
SCHEMBL6149429 0.79 ALDH1A1 (0.43) CA1CA2CA7CA9CA12
SCHEMBL6210902 0.79 CA12 (0.41) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3103 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP claimed
CN-118159542-A Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents 拜耳公司 2024-06-07 CN claimed
CN-113651863-B Unsaturated thioglycoside compound and selective synthesis method and application thereof 华东师范大学 2023-11-10 CN claimed
US-20230219964-A1 ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES SYDDANSK UNIVERSITET (DK) 2023-07-13 US claimed
US-11643476-B2 Cellulose ester and molded article thereof DAICEL CORPORATION (JP) 2023-05-09 US claimed
EP-3441133-B1 SEMIPERMEABLE MEMBRANE DAICEL CORP (JP) 2023-05-03 EP claimed
WO-2023036707-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2023-03-16 WO claimed
EP-4143172-A1 ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES Syddansk Universitet (DK) 2023-03-08 EP claimed
CN-115720579-A Antibacterial and antifungal pleuromutilin conjugates 赛丹思科大学 2023-02-28 CN claimed
CN-110551057-B Chiral 3,3-disubstituted oxindole derivative and synthesis method and application thereof 华东师范大学 2023-02-07 CN claimed
US-4198205-A SULFONIC ACID-FREE DISPERSE DYES BASF AKTIENGESELLSCHAFT (DE) 1980-04-15 US claimed
US-4192868-A ANTIINFLAMMATORY, ANALGESIC CIBA-GEIGY CORPORATION (US) 1980-03-11 US claimed
EP-0003602-A1 Pyrrolidine derivatives for use as therapeutically active substances and medicaments containing them F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1979-08-22 EP claimed
US-4122280-A DIURETIC, SALURETIC, ANTIHYPERTENSIVE BAYER AKTIENGESELLSCHAFT (DE) 1978-10-24 US claimed
US-4113872-A DIURETICS, SALURETICS, ANTIHYPERTENSIVE, ANTITHROMBOTIC AGENTS BAKER AKTIENGESELLSHAFT (DE) 1978-09-12 US claimed
US-4112109-A DIURETIC, SALURETIC, ANTIHYPERTENSIVE, ANTITHROMBOTIC BAYER AKTIENGESELLSCHAFT (DE) 1978-09-05 US claimed
US-4099011-A DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC BAYER AKTIENGESELLSCHAFT (DE) 1978-07-04 US claimed
US-4069334-A DIURETICS, HYPOTENSIVES BAYER AKTIENGESELLSCHAFT (DT) 1978-01-17 US claimed
US-3997524-A Process for the manufacture of 6'-N-alkyl derivatives of sisomicin and verdamicin; novel intermediates useful therein, and novel 6'-N-alkylverdamicins prepared thereby SCHERING CORPORATION (US) 1976-12-14 US claimed
US-3950347-A NAPHTHOLACTAM DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-13 US claimed