Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7034812 | 0.98 | LPAR3 (0.50) | LPAR3LPAR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL28629366 | 0.98 | LPAR3 (0.50) | LPAR3LPAR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL23748835 | 0.98 | LPAR3 (0.50) | LPAR3LPAR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL28559439 | 0.98 | LPAR3 (0.50) | LPAR3LPAR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL9409656 | 0.98 | LPAR3 (0.50) | LPAR3LPAR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL867712 | 0.93 | — | — | |
| SCHEMBL823794 | 0.87 | LPAR3 (0.44) | LPAR3LPAR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL347510 | 0.84 | — | — | |
| SCHEMBL5914608 | 0.82 | LPAR3 (0.50) | LPAR3LPAR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL336619 | 0.81 | ALDH1A1 (0.42) | ALDH1A1CYP3A4TSHRATMHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991000300-A1 | (CO)POLYMER MODIFICATION EMPLOYING UNSATURATED t-ALKYL PEROXY ALKENES | AKZO N.V. (NL) | 1991-01-10 | — | — | WO | disclosed |