Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.33 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15794861 | 0.85 | DAO (0.39) | DAOAURKAAURKBINCENPMCL1 | |
| SCHEMBL9234355 | 0.79 | DAO (0.45) | DAOAURKAAURKBINCENPMCL1 | |
| SCHEMBL9752760 | 0.79 | DAO (0.45) | DAOAURKAAURKBINCENPMCL1 | |
| SCHEMBL16759805 | 0.78 | DAO (0.43) | DAOAURKAAURKBINCENPMCL1 | |
| SCHEMBL5404670 | 0.78 | AURKA (0.48) | DAOAURKAAURKBINCENPMCL1 | |
| SCHEMBL174911 | 0.78 | KDM4E (0.44) | DAOAURKAAURKBINCENPMCL1 | |
| SCHEMBL9752756 | 0.78 | DAO (0.43) | DAOAURKAAURKBINCENPMCL1 | |
| SCHEMBL8712639 | 0.74 | DAO (0.41) | DAOAURKAAURKBINCENPMCL1 | |
| SCHEMBL10692239 | 0.74 | DAO (0.41) | DAOAURKAAURKBINCENPMCL1 | |
| SCHEMBL6536604 | 0.74 | DAO (0.45) | DAOAURKAAURKBINCENPMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009848-A1 | PYRIDINONES USEFUL AS ANTIATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1991-07-11 | — | — | WO | disclosed |