Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 5/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602524 | 0.88 | CHEK1 (0.51) | AURKAAURKBINCENPCHEK1DAO | |
| SCHEMBL1694688 | 0.83 | — | — | |
| SCHEMBL9234355 | 0.81 | DAO (0.45) | AURKAAURKBINCENPCHEK1DAO | |
| SCHEMBL174911 | 0.79 | KDM4E (0.44) | AURKAAURKBINCENPDAOMCL1 | |
| SCHEMBL16759805 | 0.79 | DAO (0.43) | AURKAAURKBINCENPCHEK1DAO | |
| SCHEMBL9752756 | 0.79 | DAO (0.43) | AURKAAURKBINCENPCHEK1DAO | |
| SCHEMBL9752575 | 0.78 | DAO (0.42) | AURKAAURKBINCENPCHEK1DAO | |
| SCHEMBL4602182 | 0.77 | PARP1 (0.46) | AURKAAURKBINCENPDAOMPO | |
| SCHEMBL10692239 | 0.76 | DAO (0.41) | AURKAAURKBINCENPDAOMCL1 | |
| SCHEMBL6536604 | 0.76 | DAO (0.45) | AURKAAURKBINCENPCHEK1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925792-A1 | PHOTOREACTIVE DERIVATIVE OF HYALURONIC ACID, METHOD OF PREPARATION THEREOF, 3D-CROSSLINKED DERIVATIVE OF HYALURONIC ACID, METHOD OF PREPARATION AND USE THEREOF | Contipro Biotech s.r.o. (CZ) | 2015-10-07 | — | — | EP | claimed |
| WO-2014082608-A1 | PHOTOREACTIVE DERIVATIVE OF HYALURONIC ACID, METHOD OF PREPARATION THEREOF, 3D-CROSSLINKED DERIVATIVE OF HYALURONIC ACID, METHOD OF PREPARATION AND USE THEREOF | CONTIPRO BIOTECH S.R.O. (CZ) | 2014-06-05 | — | — | WO | claimed |
| US-20230167119-A1 | DIAMINOPYRAZOLO[1,5-A]PYRIMIDINE-6-CARBONITRILE COMPOUNDS AS ADENOSINE 2A RECEPTOR AND ADENOSINE 2B RECEPTOR ANTAGONIST | Bugworks Research, Inc. | 2023-06-01 | — | — | US | disclosed |
| US-7285559-B2 | Imidazo-substituted compounds as p38 kinase inhibitors | ROCHE PALO ALTO LLC (US) | 2007-10-23 | — | — | US | disclosed |
| US-7285561-B2 | Imidazo-substituted compounds as p38 kinase inhibitors | ROCHE PALO ALTO LLC (US) | 2007-10-23 | — | — | US | disclosed |
| US-20060252783-A1 | Imidazo-substituted compounds as p38 kinase inhibitors | GOLDSTEIN DAVID M | 2006-11-09 | — | — | US | disclosed |
| US-20060252784-A1 | Imidazo-substituted compounds as P38 kinase inhibitors | GOLDSTEIN DAVID M | 2006-11-09 | — | — | US | disclosed |
| US-7081462-B2 | Imidazo-substituted compounds as p38 kinase inhibitors | ROCHE PALO ALTO LLC (US) | 2006-07-25 | — | — | US | disclosed |
| US-6949560-B2 | Imidazo-substituted compounds as p38 kinase inhibitors | ROCHE PALO ALTO LLC (US) | 2005-09-27 | — | — | US | disclosed |
| US-20050197352-A1 | Imidazo-substituted compounds as p38 kinase inhibitors | GOLDSTEIN DAVID M (US) | 2005-09-08 | — | — | US | disclosed |
| US-20030232847-A1 | Imidazo-substituted compounds as p38 kinase inhibitors | ROCHE PALO ALTO LLC | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252784-A1 | Imidazo-substituted compounds as P38 kinase inhibitors | MAPK1, MAP3K1, MAPK3 | AURKA 361/4885AURKB 330/4885INCENP 2585/4885 |
| US-20060252783-A1 | Imidazo-substituted compounds as p38 kinase inhibitors | MAPK1, MAP3K1, MAPK3 | AURKA 361/4885AURKB 330/4885INCENP 2585/4885 |
| US-20050197352-A1 | Imidazo-substituted compounds as p38 kinase inhibitors | MAPK1, MAP3K1, MAPK3 | AURKA 361/4885AURKB 330/4885INCENP 2585/4885 |
| US-20230167119-A1 | DIAMINOPYRAZOLO[1,5-A]PYRIMIDINE-6-CARBONITRILE COMPOUNDS AS ADENOSINE 2A RECEPTOR AND ADENOSINE 2B RECEPTOR ANTAGONIST | ADORA2A, ADORA2B, ADORA1 | AURKA 544/4885AURKB 534/4885INCENP 3901/4885 |
| US-20030232847-A1 | Imidazo-substituted compounds as p38 kinase inhibitors | MAPK1, MAPK3, MAP3K1 | AURKA 229/4885AURKB 301/4885INCENP 1716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.