Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752434 | 0.86 | TSHR (0.32) | TSHR | |
| SCHEMBL9752483 | 0.82 | TSHR (0.38) | TSHRALDH1A1 | |
| SCHEMBL9752473 | 0.72 | CYP3A4 (0.32) | TSHRCYP3A4 | |
| SCHEMBL1982082 | 0.72 | DNM1 (0.36) | TSHRALDH1A1LMNACYP3A4SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL3119315 | 0.71 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL9737608 | 0.71 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL8441962 | 0.71 | TSHR (0.34) | TSHRALDH1A1 | |
| SCHEMBL9752690 | 0.68 | TSHR (0.33) | TSHRALDH1A1 | |
| SCHEMBL3119319 | 0.68 | TSHR (0.36) | TSHRALDH1A1 | |
| SCHEMBL3112090 | 0.68 | TSHR (0.36) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991000300-A1 | (CO)POLYMER MODIFICATION EMPLOYING UNSATURATED t-ALKYL PEROXY ALKENES | AKZO N.V. (NL) | 1991-01-10 | — | — | WO | disclosed |