Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 10/20 | 0.42 |
| ▸ | CTSS | P25774 | 6/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27507325 | 1.00 | MEN1 (0.44) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL7430206 | 1.00 | MEN1 (0.44) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL9753575 | 0.90 | CA1 (0.44) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL5031624 | 0.87 | CA1 (0.45) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL10772880 | 0.83 | CTSK (0.56) | CTSKCTSS | |
| SCHEMBL7221421 | 0.83 | CTSK (0.56) | CTSKCTSS | |
| SCHEMBL18866617 | 0.82 | CA1 (0.46) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL9396774 | 0.82 | CA1 (0.46) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL27490793 | 0.82 | MEN1 (0.45) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL3431559 | 0.81 | CTSK (0.51) | MEN1GAAKMT2ACTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008737-A2 | PHARMACOLOGICALLY ACTIVE AMIDE CARBOXYLATE DERIVATIVES | FISONS PLC (GB) | 1991-06-27 | — | — | WO | disclosed |