Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753011 | 1.00 | MAPK14 (0.43) | MAPK14EGFRRAF1ADORA3ADORA2A | |
| SCHEMBL9752969 | 0.87 | MAPK14 (0.47) | MAPK14EGFRRAF1ADORA3ADORA2A | |
| SCHEMBL9753157 | 0.85 | MAPK14 (0.41) | MAPK14EGFRRAF1ADORA3ADORA2A | |
| SCHEMBL9753675 | 0.85 | MAPK14 (0.41) | MAPK14EGFRRAF1ADORA3ADORA2A | |
| SCHEMBL9753678 | 0.85 | MAPK14 (0.41) | MAPK14EGFRRAF1ADORA3ADORA2A | |
| SCHEMBL9753160 | 0.85 | MAPK14 (0.41) | MAPK14EGFRRAF1ADORA3ADORA2A | |
| SCHEMBL9753659 | 0.81 | MAPK14 (0.40) | MAPK14EGFRRAF1ADORA3ADORA2A | |
| SCHEMBL9753655 | 0.81 | MAPK14 (0.40) | MAPK14EGFRRAF1ADORA3ADORA2A | |
| SCHEMBL18854064 | 0.76 | MAPK14 (0.61) | MAPK14EGFRRAF1ADORA3ADORA2A | |
| SCHEMBL9753212 | 0.75 | MAPK14 (0.41) | MAPK14EGFRRAF1ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |