Acrylamide

Acrylamide

SCHEMBL9753028

C=CC(N)=O.CCOCC.O=C(O)CO

nearest known ligand 0.46

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Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.46
ALDH1A1 P00352 6/20 0.46
FGFR4 P22455 1/20 0.46
ALOX15 P16050 1/20 0.34
HPGD P15428 1/20 0.31
FFAR3 O14843 1/20 0.31
LMNA P02545 1/20 0.31
THRB P10828 2/20 0.31
TP53 P04637 2/20 0.30
HIF1A Q16665 2/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylamide SCHEMBL7033416 0.89 ALDH1A1 (0.58) TSHRALDH1A1FGFR4ALOX15HPGD
Acrylamide SCHEMBL10783907 0.89 ALDH1A1 (0.58) TSHRALDH1A1FGFR4ALOX15HPGD
Acrylic Acid SCHEMBL2305630 0.87 TSHR (0.50) TSHRALDH1A1FGFR4ALOX15HPGD
Acrylamide SCHEMBL27755765 0.87 ALDH1A1 (0.55) TSHRALDH1A1FGFR4ALOX15HPGD
Acrylamide SCHEMBL28639446 0.85 TSHR (0.52) TSHRALDH1A1FGFR4ALOX15HPGD
Acrylamide SCHEMBL28639445 0.84 TSHR (0.58) TSHRALDH1A1FGFR4ALOX15FFAR3
Acrylamide SCHEMBL725526 0.84 ALDH1A1 (0.65) TSHRALDH1A1FGFR4ALOX15LMNA
Acrylamide SCHEMBL28002782 0.83 TSHR (0.50) TSHRALDH1A1FGFR4ALOX15HPGD
Acrylamide SCHEMBL17599557 0.82 TSHR (0.61) TSHRALDH1A1FGFR4ALOX15LMNA
Ether SCHEMBL251857 0.82 FFAR3 (0.44) TSHRALDH1A1ALOX15FFAR3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3179037-A None JP disclosed
CN-109776837-B Prevent blue light protection film 合肥乐凯科技产业有限公司 2021-07-06 CN disclosed
JP-H03179037-A ONE-PACK SURFACE TREATMENT FOR POLYVINYL CHLORIDE NIPPON SHOKUBAI KAGAKU KOGYO CO LTD 1991-08-05 JP disclosed
EP-0334643-A1 Fluorocarbon polymer compositions and methods HOECHST CELANESE CORPORATION (US) 1989-09-27 EP disclosed