Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 6/20 | 0.61 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CLK2 | P49760 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9757232 | 0.86 | TOP2A (0.53) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL8094873 | 0.84 | TOP2A (0.60) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL9520197 | 0.84 | TOP2A (0.60) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL10337934 | 0.84 | TOP2A (0.62) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| Acridine SCHEMBL9790165 | 0.83 | TOP2A (0.61) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL500719 | 0.81 | TOP2A (0.71) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL29463823 | 0.81 | TOP2A (0.71) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL10785816 | 0.81 | TOP2A (0.62) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL9668066 | 0.81 | TOP2A (0.62) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL9519028 | 0.81 | TOP2A (0.64) | TOP2ATOP2BALDH1A1POLBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3181478-A | — | — | None | — | — | JP | disclosed |
| JP-H03181478-A | PYRIDINECARBOXYLIC ACID DERIVATIVE | BANYU PHARMACEUT CO LTD | 1991-08-07 | — | — | JP | disclosed |