Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 11/20 | 0.62 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | NPPA | P01160 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753127 | 1.00 | MME (0.62) | MMEACENPPAECE1MMP2 | |
| SCHEMBL9753909 | 0.89 | MME (0.47) | MMEACENPPAECE1MMP2 | |
| SCHEMBL9753450 | 0.89 | MME (0.47) | MMEACENPPAECE1MMP2 | |
| SCHEMBL9753510 | 0.86 | MME (0.64) | MMEACENPPAECE1MMP2 | |
| SCHEMBL9753506 | 0.86 | MME (0.64) | MMEACENPPAECE1MMP2 | |
| SCHEMBL5924879 | 0.77 | MME (1.00) | MME | |
| SCHEMBL5925045 | 0.77 | MME (0.79) | MME | |
| SCHEMBL5924893 | 0.77 | MME (0.79) | MME | |
| SCHEMBL9753893 | 0.76 | MME (0.65) | MMEACENPPAECE1MMP2 | |
| SCHEMBL9753889 | 0.76 | MME (0.65) | MMEACENPPAECE1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991010644-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE DIURETIC AGENTS | PFIZER LIMITED (GB) | 1991-07-25 | — | — | WO | disclosed |