Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 0.65 |
| ▸ | ACE | P12821 | 3/20 | 0.65 |
| ▸ | ECE1 | P42892 | 2/20 | 0.65 |
| ▸ | NPPA | P01160 | 1/20 | 0.65 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753893 | 1.00 | MME (0.65) | MMEACEECE1NPPACPB2 | |
| SCHEMBL9753506 | 0.90 | MME (0.64) | MMEACEECE1NPPACPB2 | |
| SCHEMBL9753510 | 0.90 | MME (0.64) | MMEACEECE1NPPACPB2 | |
| SCHEMBL9753450 | 0.86 | MME (0.47) | MMEACEECE1NPPAMMP2 | |
| SCHEMBL9753909 | 0.86 | MME (0.47) | MMEACEECE1NPPAMMP2 | |
| Sampatrilat SCHEMBL49066 | 0.79 | ECE1 (1.00) | MMEACEECE1NPPACPB2 | |
| Sampatrilat SCHEMBL4567110 | 0.79 | ECE1 (1.00) | MMEACEECE1NPPACPB2 | |
| Sampatrilat SCHEMBL7301333 | 0.79 | ECE1 (1.00) | MMEACEECE1NPPACPB2 | |
| SCHEMBL7294367 | 0.78 | ACE (0.91) | MMEACEECE1NPPAITGB3 | |
| SCHEMBL7294361 | 0.78 | MME (0.80) | MMEACEECE1NPPAMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991010644-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE DIURETIC AGENTS | PFIZER LIMITED (GB) | 1991-07-25 | — | — | WO | claimed |