SCHEMBL9753410

SCHEMBL9753410

Cc1ccc(S)c(C(=O)c2ccccc2)c1

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.51
POLB P06746 1/20 0.51
NPSR1 Q6W5P4 1/20 0.50
TP53 P04637 2/20 0.49
GAA P10253 1/20 0.49
NPC1 O15118 1/20 0.49
MAPT P10636 1/20 0.49
MAPK1 P28482 1/20 0.49
HTT P42858 1/20 0.49
PKM P14618 1/20 0.48
KDM4E B2RXH2 1/20 0.47
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
BCL2 P10415 1/20 0.45
MCL1 Q07820 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14189061 0.86 AKR1C3 (0.51) AKR1C3POLBNPSR1TP53GAA
SCHEMBL28384878 0.83 AKR1C3 (0.61) AKR1C3POLBNPSR1TP53GAA
SCHEMBL305558 0.81 NPSR1 (0.60) AKR1C3POLBNPSR1TP53GAA
SCHEMBL29356028 0.81 NPSR1 (0.60) AKR1C3POLBNPSR1TP53GAA
Toluene SCHEMBL23929056 0.80 AKR1C3 (0.58) AKR1C3POLBNPSR1GAANPC1
SCHEMBL147250 0.80 CSNK2A1 (0.63) AKR1C3POLBNPSR1GAAMAPT
SCHEMBL31366618 0.80 MAPT (0.73) AKR1C3POLBNPSR1TP53GAA
SCHEMBL9217336 0.80 AKR1C3 (0.68) AKR1C3POLBNPSR1TP53NPC1
SCHEMBL5383825 0.80 MAPT (0.73) AKR1C3POLBNPSR1TP53GAA
6-Benzoyl-3-Methylbenzoic Acid SCHEMBL5309754 0.80 AKR1C3 (0.68) AKR1C3POLBNPSR1TP53NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991007380-A1 ARTHROPODICIDES DUNLENA PTY. LTD. (AU) 1991-05-30 WO disclosed