⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28051607 | 0.79 | — | — | |
| SCHEMBL17628495 | 0.71 | — | — | |
| SCHEMBL148930 | 0.69 | MEN1 (0.47) | — | |
| SCHEMBL6995759 | 0.69 | — | — | |
| SCHEMBL8543447 | 0.69 | — | — | |
| SCHEMBL132519 | 0.69 | MEN1 (0.38) | — | |
| SCHEMBL35120 | 0.69 | — | — | |
| SCHEMBL8887906 | 0.67 | MEN1 (0.37) | — | |
| SCHEMBL11509672 | 0.67 | ALDH1A1 (0.33) | — | |
| SCHEMBL25218451 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991007485-A1 | IMPROVED BIOREACTOR SURFACES AND METHODS OF MAKING SAME | BIO-METRIC SYSTEMS, INC. (US) | 1991-05-30 | — | — | WO | disclosed |
| US-4415668-A | Cell culture | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1983-11-15 | — | — | US | disclosed |
| US-4293654-A | CROSSLINGING DEXTRAN BEADS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1981-10-06 | — | — | US | disclosed |
| US-4189534-A | Cell culture microcarriers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1980-02-19 | — | — | US | disclosed |