Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.88 |
| ▸ | NPC1 | O15118 | 2/20 | 0.88 |
| ▸ | GRM5 | P41594 | 9/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.78 |
| ▸ | ATM | Q13315 | 1/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13296220 | 0.93 | GRM5 (0.82) | RAB9ANPC1GRM5KMT2ASMN1; SMN2 | |
| SCHEMBL23367929 | 0.88 | GRM5 (0.75) | RAB9ANPC1GRM5KMT2ASMN1; SMN2 | |
| SCHEMBL821839 | 0.87 | KMT2A (1.00) | RAB9ANPC1GRM5KMT2AATM | |
| SCHEMBL28327587 | 0.87 | RXFP1 (0.78) | RAB9ANPC1GRM5KMT2ASMN1; SMN2 | |
| SCHEMBL28326270 | 0.85 | GRM5 (0.76) | RAB9ANPC1GRM5KMT2ASMN1; SMN2 | |
| SCHEMBL8557860 | 0.85 | GRM5 (1.00) | RAB9ANPC1GRM5 | |
| SCHEMBL14742370 | 0.85 | NPC1 (0.85) | RAB9ANPC1GRM5KMT2AATM | |
| SCHEMBL21652317 | 0.84 | GRM5 (0.69) | RAB9ANPC1GRM5KMT2ASMN1; SMN2 | |
| SCHEMBL31725239 | 0.83 | RAB9A (0.78) | RAB9ANPC1GRM5KMT2AMEN1 | |
| SCHEMBL3119185 | 0.83 | RAB9A (0.78) | RAB9ANPC1GRM5KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016004272-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | PHARMACYCLICS LLC (US) | 2016-01-07 | — | — | WO | claimed |
| CN-116462661-A | Deuterated 3- (pyridin-4-yl) propionic acid compound, and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-109053558-B | Synthesis method of N-heterocyclic amide derivative | 贵州大学 | 2022-02-18 | — | — | CN | disclosed |
| CN-113735850-A | Synthesis method of 1,2, 4-triazole compound | 河南师范大学 | 2021-12-03 | — | — | CN | disclosed |
| WO-2016004272-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | PHARMACYCLICS LLC (US) | 2016-01-07 | — | — | WO | disclosed |
| US-8192918-B2 | Lithographic printing plate precursor | AGFA GRAPHICS NV (BE) | 2012-06-05 | — | — | US | disclosed |
| US-8192918-B2 | Lithographic printing plate precursor | AGFA GRAPHICS NV (BE) | 2012-06-05 | — | — | US | disclosed |
| US-20100112476-A1 | A LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA GRAPHICS NV (BE) | 2010-05-06 | — | — | US | disclosed |
| US-20100112476-A1 | A LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA GRAPHICS NV (BE) | 2010-05-06 | — | — | US | disclosed |
| WO-2008132091-A1 | A LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA GRAPHICS NV (BE) | 2008-11-06 | — | — | WO | disclosed |
| EP-1985445-A1 | A lithographic printing plate precursor | Agfa Graphics N.V. (BE) | 2008-10-29 | — | — | EP | disclosed |
| WO-1991017979-A1 | PROCESS FOR THE PREPARATION OF 2-N-ACYLAMINOPYRIDINES AND 2-AMINOPYRIDINES FROM 5-OXOALKANENITRILE OXIMES | DSM N.V. (NL) | 1991-11-28 | — | — | WO | disclosed |